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. 1995 Sep;2(9):733-5.
doi: 10.1038/nsb0995-733.

Crystal structures of B-form DNA-RNA chimers complexed with distamycin

X Chen, B Ramakrishnan, M Sundaralingam

Crystal structures of B-form DNA-RNA chimers complexed with distamycin

X Chen et al. Nat Struct Biol. 1995 Sep.

Abstract

Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

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