Mutations in GltC that increase Bacillus subtilis gltA expression
- PMID: 7559360
- PMCID: PMC177382
- DOI: 10.1128/jb.177.19.5696-5700.1995
Mutations in GltC that increase Bacillus subtilis gltA expression
Abstract
Mutants with altered forms of GltC, a positive LysR-type regulator of Bacillus subtilis glutamate synthase gene expression, were isolated. The mutant GltC proteins stimulated expression from the wild-type gltA promoter region 1.5- to 2.0-fold and from mutant promoter regions up to 80-fold. Moreover, expression of gltA became much less dependent on a nitrogen source-associated signal.
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