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Comparative Study
. 1995 Nov;154(5):1665-9.
doi: 10.1016/s0022-5347(01)66743-0.

Clinical and biochemical presentation of gouty diathesis: comparison of uric acid versus pure calcium stone formation

J Khatchadourian  1 , G M Preminger, P A Whitson, B Adams-Huet, C Y Pak
Affiliations
Comparative Study

Clinical and biochemical presentation of gouty diathesis: comparison of uric acid versus pure calcium stone formation

J Khatchadourian et al. J Urol. 1995 Nov.

Abstract

Purpose: We compared gouty diathesis with uric acid versus calcium stones.

Materials and methods: We retrospectively reviewed clinical and laboratory data from 95 gouty diathesis patients (28 with uric acid and 67 with calcium stones) and 99 normal subjects.

Results: Of the gouty diathesis patients gouty arthritis was present in 21% of those with uric acid and 12% of those with calcium stones. Hyperuricemia developed in 43% of those with uric acid and 27% of those with calcium stones, and 2% of controls. Urinary pH was independent of the net gastrointestinal absorption of alkali in the gouty diathesis groups. Urinary pH and citrate increased after potassium citrate treatment.

Conclusions: The characteristic features of primary gout were present in both gouty diathesis groups and both are responsive to treatment.

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