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. 1995 Nov;154(5):1681-4.
doi: 10.1016/s0022-5347(01)66749-1.

Vein invasion in renal cell carcinoma: impact on metastatic behavior and survival

B Ljungberg  1 , R Stenling, B Osterdahl, E Farrelly, T Aberg, G Roos
Affiliations

Vein invasion in renal cell carcinoma: impact on metastatic behavior and survival

B Ljungberg et al. J Urol. 1995 Nov.

Abstract

Purpose: The development of a thrombus extending into the veins is well recognized in renal cell carcinoma. We investigated the hypothesis that vein invasion alone has no adverse impact on survival but is a highly negative factor in other tumors.

Materials and methods: In 200 consecutive patients invasion of the renal vein and vena cava was evaluated and compared with the clinical course.

Results: A total of 26 patients had vena caval and 47 had renal vein invasion. Patients with venous invasion had a significantly shorter survival but no survival difference was demonstrated based on the level of involvement.

Conclusions: Our study indicates that vein invasion itself seems to be an important prognostic factor in renal cell carcinoma.

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