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. 1995 Aug;47(2):49-53.
doi: 10.1016/0300-2977(95)00038-o.

Idiopathic haemochromatosis: magnetic resonance signal intensity ratios permit non-invasive diagnosis of low levels of iron overload

J D Macfarlane  1 , G R Vreugdenhil, J Doornbos, G B van der Voet
Affiliations

Idiopathic haemochromatosis: magnetic resonance signal intensity ratios permit non-invasive diagnosis of low levels of iron overload

J D Macfarlane et al. Neth J Med. 1995 Aug.

Abstract

Objective: The detection of low levels of iron overload by magnetic resonance imaging.

Methods: Eight consecutive patients suspected of having idiopathic haemochromatosis. Comparison of signal intensity ratios and absolute iron content of liver.

Results: There was a good correlation between the signal intensity ratios and iron content in the range 2-30 micrograms Fe/mg dry weight.

Conclusions: The ability of a non-invasive technique to detect low levels of iron overload could be useful in the assessment of therapy and in the screening of relatives of probands with idiopathic haemochromatosis.

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