Site dependence of postmortem blood methadone concentrations
- PMID: 7572883
- DOI: 10.1097/00000433-199506000-00002
Site dependence of postmortem blood methadone concentrations
Abstract
A case investigated by the Office of the Chief Medical Examiner, State of Maryland, identified methadone at a heart blood concentration of 2.4 mg/L and a subclavian blood concentration of 0.8 mg/L. Due to these discrepant results, a study was undertaken to determine whether such inconsistencies occurred in other methadone cases. Of the 15 cases studied, only four had heart blood and alternate blood concentrations within 20% of one another. In only 53% of the cases were variations of < 60% observed. The data failed to show a trend where one site was consistently higher or lower than the other site.
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