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Case Reports
. 1995 Oct;57(4):840-5.

Autosomal dominant zonular cataract with sutural opacities localized to chromosome 17q11-12

T Padma  1 , R Ayyagari, J S Murty, S Basti, T Fletcher, G N Rao, M Kaiser-Kupfer, J F Hejtmancik
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Case Reports

Autosomal dominant zonular cataract with sutural opacities localized to chromosome 17q11-12

T Padma et al. Am J Hum Genet. 1995 Oct.

Abstract

Congenital cataracts constitute a morphologically and genetically heterogeneous group of diseases that are a major cause of childhood blindness. Different loci for hereditary congenital cataracts have been mapped to chromosomes 1, 2, 16, and 17q24. We report linkage of a gene causing a unique form of autosomal dominant zonular cataracts with Y-sutural opacities to chromosome 17q11-12 in a three-generation family exhibiting a maximum lod score of 3.9 at D17S805. Multipoint analysis gave a 1-lod confidence interval of 17 cM. This interval is bounded by the markers D17S799 and D17S798, a region that would encompass a number of candidate genes including that coding for beta A3/A1-crystallin.

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References

    1. Ann Hum Genet. 1967 Aug;31(1):45-50 - PubMed
    1. Ann Hum Genet. 1963 Aug;27:67-84 - PubMed
    1. Cytogenet Cell Genet. 1978;22(1-6):295-7 - PubMed
    1. Nature. 1983 Mar 31-Apr 6;302(5907):415-7 - PubMed
    1. Am J Hum Genet. 1984 Mar;36(2):460-5 - PubMed

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