Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Sep;53(3):228-32.
doi: 10.4269/ajtmh.1995.53.228.

Detection of hepatitis E virus infections among domestic swine in the Kathmandu Valley of Nepal

E T Clayson  1 , B L Innis, K S Myint, S Narupiti, D W Vaughn, S Giri, P Ranabhat, M P Shrestha
Affiliations

Detection of hepatitis E virus infections among domestic swine in the Kathmandu Valley of Nepal

E T Clayson et al. Am J Trop Med Hyg. 1995 Sep.

Abstract

The prevalence of hepatitis E virus (HEV) infections among 55 domestic swine living in the Kathmandu Valley of Nepal was investigated. Sera and stool specimens were collected from 47 free-roaming swine and examined for the presence of HEV genomic sequences by the reverse transcription-polymerase chain reaction. Sera from these animals, as well as sera from eight other swine, were also examined for the presence of HEV-specific antibodies by an enzyme-linked immunosorbent assay and by a fluorescent antibody blocking assay. Hepatitis E virus RNA was detected in the sera and/or stool of three of 47 swine, while HEV-specific antibodies were detected in 18 of 55 swine. These results indicate that HEV is a zoonotic virus, and that swine are among its natural hosts.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources