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Review
. 1995 Oct;16(10):469-73.
doi: 10.1016/0167-5699(95)80029-8.

Murine CD38: an immunoregulatory ectoenzyme

F Lund  1 , N Solvason, J C Grimaldi, R M Parkhouse, M Howard
Affiliations
Review

Murine CD38: an immunoregulatory ectoenzyme

F Lund et al. Immunol Today. 1995 Oct.

Abstract

CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.

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