Review
doi: 10.1159/000237177.
Features of oral immunization
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- PMID: 7580304
- DOI: 10.1159/000237177
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Review
Features of oral immunization
Int Arch Allergy Immunol.
1995 Dec.
Abstract
In this review, we focus on some key areas concerning the unique properties of the mucosal immune system. They are: (1) the fact that the common mucosal immune system consists of different compartments; (2) the advantages of oral vaccination, which can be exploited to antigen-specific sIgA-mediated local immune responses as well as systemic immunity; (3) efficacious oral immunization against respiratory infections; (4) oral tolerance with respect to activation of T cells which, after declining, can be repeatedly reinduced without changes in profile or magnitude, and (5) the use of transgenic plants as a new vaccine source for a new vaccination strategy, i.e. employing edible dietary vaccines.
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