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Review
. 1995 Aug 1;5(8):854-8.
doi: 10.1016/s0960-9822(95)00172-2.

Proteolysis. The proteasome: a protein-degrading organelle?

D M Rubin  1 , D Finley
Affiliations
Free article
Review

Proteolysis. The proteasome: a protein-degrading organelle?

D M Rubin et al. Curr Biol. .
Free article

Abstract

The crystal structure of the proteasome suggests that degradation of ubiquitin-protein conjugates is achieved by unfolding the protein substrate and translocating it through a channel into a peptidase-containing chamber.

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