Proteolysis. The proteasome: a protein-degrading organelle?
- PMID: 7583140
- DOI: 10.1016/s0960-9822(95)00172-2
Proteolysis. The proteasome: a protein-degrading organelle?
Abstract
The crystal structure of the proteasome suggests that degradation of ubiquitin-protein conjugates is achieved by unfolding the protein substrate and translocating it through a channel into a peptidase-containing chamber.
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