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Review
. 1995 Aug 1;5(8):859-61.
doi: 10.1016/s0960-9822(95)00173-4.

Transcriptional regulation. Flipping the Myc switch

R Bernards  1
Affiliations
Free article
Review

Transcriptional regulation. Flipping the Myc switch

R Bernards. Curr Biol. .
Free article

Abstract

When certain cells differentiate, Myc in Myc-Max heterodimers is replaced by Mad or Mxi, generating heterodimers that suppress transcription by interacting with the repressor Sin3.

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