Unique ionic mechanism of action of ibutilide on freshly isolated heart cells
- PMID: 7586381
Unique ionic mechanism of action of ibutilide on freshly isolated heart cells
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Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. Concentration-, time-, voltage-, and use-dependent effects.Circulation. 1995 Mar 15;91(6):1799-806. doi: 10.1161/01.cir.91.6.1799. Circulation. 1995. PMID: 7882490
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