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Case Reports
. 1995 Jul;14(4):474-7.
doi: 10.1007/BF02207686.

Ochronotic arthropathy: rapid destructive hip osteoarthritis associated with metabolic disease

T Corrà  1 , M Zaccala, M Galante
Affiliations
Case Reports

Ochronotic arthropathy: rapid destructive hip osteoarthritis associated with metabolic disease

T Corrà et al. Clin Rheumatol. 1995 Jul.

Abstract

Ochronosis is a musculoskeletal manifestation of alkaptonuria, an inherited metabolic disorder associated with various systemic abnormalities related to the deposition of homogentisic acid pigment in connective tissues. This report describes a 58-year-old woman with ochronotic arthropathy who, in addition to the typical clinical features of the disorder, presented with rapidly progressive hip osteoarthritis. The destruction of the joint architecture and the severe functional impairment necessitated a total hip replacement which resulted in a satisfactory outcome.

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