Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Feb;25(2):137-42.
doi: 10.1002/cpt1979252137.

Bromocriptine inhibits norepinephrine release

M G Ziegler, C R Lake, A C Williams, P F Teychenne, I Shoulson, O Steinsland

Bromocriptine inhibits norepinephrine release

M G Ziegler et al. Clin Pharmacol Ther. 1979 Feb.

Abstract

Bromocriptine is a dopamine agonist that induces postural hypotension and can be used as an antihypertensive. The drug inhibits release of norepinephrine (NE) from an isolated artery by stimulating presynaptic receptors. In normotensive subjects it lowers both plasma and cerebrospinal fluid (CSF) levels of NE by 50% and lowers blood pressure moderately in standing subjects and slightly in recumbent subjects. Through central and peripheral mechanisms, bromocriptine inhibits sympathetic nervous discharge of NE.

PubMed Disclaimer

Publication types