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Comparative Study
. 1995 Sep;48(9):967-72.
doi: 10.7164/antibiotics.48.967.

Sattabacins and sattazolins: new biologically active compounds with antiviral properties extracted from a Bacillus sp

G Lampis  1 , D Deidda, C Maullu, M A Madeddu, R Pompei, F Delle Monachie, G Satta
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Free article
Comparative Study

Sattabacins and sattazolins: new biologically active compounds with antiviral properties extracted from a Bacillus sp

G Lampis et al. J Antibiot (Tokyo). 1995 Sep.
Free article

Abstract

A series of new compounds with antiviral properties were isolated from a Bacillus sp. strain B-60. They were named sattabacin (1), hydroxysattabacin (2), sattazolin (3) and methylsattazolin (4). The biologically active compounds were recovered from fermentation broth by ethyl acetate extraction and silica-gel column fractionation. Their antiviral activity was mainly expressed against the Herpes simplex viruses type 1 and 2. The compound 3 showed a selective inhibition of protein synthesis in Herpesvirus-infected cells.

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