Amyloidosis of the head and neck. A clinicopathologic study of the UCLA experience, 1955-1991
- PMID: 7598857
- DOI: 10.1001/archotol.1995.01890070064014
Amyloidosis of the head and neck. A clinicopathologic study of the UCLA experience, 1955-1991
Abstract
Objective: To characterize the otolaryngologic manifestations of amyloidosis; classify patients with amyloidosis by specific location and type of underlying disease; and compare disease presentation and long-term outcome in these patients.
Design: Retrospective review of biopsy specimens recorded as amyloidosis.
Setting: Tertiary care referral center serving a diverse patient base.
Patients: Of 141 patients with biopsy-verified amyloidosis who met the inclusion criterion for the study, 27 (19%) had head and neck manifestations.
Outcome measures: Good functional outcome and survival of patients with amyloidosis.
Results: The tongue was the most commonly affected site of the head and neck. Distinct differences exist in functional outcome and long-term survival in patients with the localized form of amyloidosis when compared with patients with systemic amyloidosis.
Conclusion: Because amyloidosis often affects the head and neck, otolaryngologists need to be familiar with this disease.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
