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. 1995;107(4):216-8.
doi: 10.1007/BF01428410.

A HinfI polymorphism in the 5' flanking region of the human VNTR locus D1S80

A Alonso  1 , P Martin, C Albarrán, M Sancho
Affiliations

A HinfI polymorphism in the 5' flanking region of the human VNTR locus D1S80

A Alonso et al. Int J Legal Med. 1995.

Abstract

A restriction fragment length polymorphism (RFLP) characterized by the presence (HinfI+) or absence (HinfI-) of a HinfI site has been found in the 5' flanking region of the VNTR locus D1S80. RFLP-allele frequencies were determined from 82 unrelated individuals: HinfI+ = 0.49, HinfI- = 0.51. The RFLP/VNTR haplotype frequencies show an absolute association between the HinfI+ allele and the VNTR allele of 18 repeat units and an extreme association between the HinfI- allele and the VNTR allele of 24 repeat units. The remaining VNTR alleles associate more randomly with the 2 flanking HinfI alleles.

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