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Case Reports
. 1995 May;70(5):279-80.
doi: 10.1007/BF01784049.

An unwanted side effect of hydroxyurea in a patient with idiopathic myelofibrosis

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Case Reports

An unwanted side effect of hydroxyurea in a patient with idiopathic myelofibrosis

M J Starmans-Kool et al. Ann Hematol. 1995 May.

Abstract

A patient with idiopathic myelofibrosis is reported who developed a drug fever after treatment with hydroxyurea, a generally effective and well-tolerated drug in chronic myeloproliferative syndromes. Typically, this form of fever develops after a few weeks of exposure to the drug and disappears with discontinuation of the drug. Possible interactions with prostaglandin or leukotriene metabolism may play a role.

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