Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jan;94(1):65-74.

The resistance of spontaneous mouse hepatocellular neoplasms to iron accumulation during rapid iron loading by parenteral administration and their transplantability

G M Williams, N Hirota, J M Rice

The resistance of spontaneous mouse hepatocellular neoplasms to iron accumulation during rapid iron loading by parenteral administration and their transplantability

G M Williams et al. Am J Pathol. 1979 Jan.

Abstract

Spontaneous mouse liver nodules were found to be resistant to iron accumulation induced either by dietary overload or by a rapid protocol of subcutaneous injection of iron dextran. Transplants of 11 liver nodules into the mammary fat pad gave rise to neoplastic growth. Transplants of the less differentiated nodules grew more frequently and rapidly than better differentiated nodules and produced pulmonary metastases. Therefore, these mouse liver nodules are considered to be neoplasms, and their resistance to iron accumulation suggests that this marker will be useful in studying their histogenesis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Natl Cancer Inst. 1952 Oct;13(2):455-503 - PubMed
    1. Am J Pathol. 1977 Nov;89(2):379-90 - PubMed
    1. Cancer Res. 1978 Jul;38(7):2003-10 - PubMed
    1. J Natl Cancer Inst. 1978 Jul;61(1):113-21 - PubMed
    1. J Natl Cancer Inst. 1976 Jul;57(1):157-65 - PubMed

Publication types

LinkOut - more resources