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. 1995 Apr 10;26(3):595-8.
doi: 10.1016/0888-7543(95)80181-k.

Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue

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Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue

K L Puranam et al. Genomics. .

Abstract

We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.

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