Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue
- PMID: 7607686
- DOI: 10.1016/0888-7543(95)80181-k
Chromosomal localization of the gene encoding the human DNA helicase RECQL and its mouse homologue
Abstract
We have determined the chromosomal location of the human and mouse genes encoding the RECQL protein, a putative DNA helicase homologous to the bacterial DNA helicase, RecQ. RECQL was localized to human chromosome 12 by analysis of human-rodent somatic cell hybrid DNA; fine mapping of RECQL by fluorescence in situ hybridization revealed its chromosomal location to be 12p11-p12. The corresponding mouse gene, Recql, was mapped to the telomeric end of mouse chromosome 6 by analysis of DNA from an interspecific cross.
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