Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1995 Aug;154(2 Pt 1):540-5.
doi: 10.1097/00005392-199508000-00065.

The role of surgery in the management of pediatric pelvic rhabdomyosarcoma

S P Lerner  1 , A Hayani, P O'Hollaren, C Winkel, M Ohori, F J Harberg, D R Roth, E T Gonzales Jr
Affiliations
Review

The role of surgery in the management of pediatric pelvic rhabdomyosarcoma

S P Lerner et al. J Urol. 1995 Aug.

Abstract

Purpose: We assessed the role of surgery, particularly exenteration, in the treatment of children with lower urinary tract and pelvic rhabdomyosarcoma.

Materials and methods: We treated 23 children with bladder and/or prostate (11), or pelvic retroperitoneal tumors (12). Initial management was tumor resection in 6 cases, anterior pelvic exenteration in 5 and biopsy only in 12, combined with chemotherapy in 23 and radiotherapy in 20.

Results: The bladder salvage rate for surviving patients with pelvic tumors was 92% versus 27% for those with prostate/bladder tumors. Estimated 5 and 10-year survival probability for patients with pelvic retroperitoneal tumors was 49 +/- 50% compared to 81 +/- 24% for those with bladder and/or prostate tumors (log rank test, p = 0.11).

Conclusions: Exenterative surgery is frequently required to achieve a durable complete response.

PubMed Disclaimer

MeSH terms