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Review
. 1995 Apr;7(2):211-4.
doi: 10.1016/0955-0674(95)80030-1.

Molecular control of life and death

J Yuan  1
Affiliations
Review

Molecular control of life and death

J Yuan. Curr Opin Cell Biol. 1995 Apr.

Abstract

Recent evidence has shown that two of the three key genes in the programmed cell death pathway of Caenorhabditis elegans, ced-9 (a cell death suppressor) and ced-3 (a cell death inducer), encode proteins that share structural and functional similarities with the mammalian proto-oncogene product Bcl-2 and interleukin-1 beta converting enzyme, respectively. These findings reveal key molecules that control life and death decisions in vertebrates.

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