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Review
. 1995 Apr;3(4):159-62.
doi: 10.1016/s0966-842x(00)88908-8.

Is rotavirus a population of reassortants?

V Gouvea  1 , M Brantly
Affiliations
Review

Is rotavirus a population of reassortants?

V Gouvea et al. Trends Microbiol. 1995 Apr.

Abstract

Rotaviruses appear to exist as heterogeneous populations of reassortants and related variants. This phenomenon is consistent with the quasispecies concept of RNA viruses, and suggests that gene reassortment is a crucial evolutionary mechanism for this segmented virus. It also explains puzzling epidemiological findings and controversial results of vaccine-efficacy studies.

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