Combined radioprotective effect of Broncho-Vaxom and WR-2721 on hemopoiesis and circulating blood cells
- PMID: 7617070
Combined radioprotective effect of Broncho-Vaxom and WR-2721 on hemopoiesis and circulating blood cells
Abstract
Possibilities of combined radioprotection, using preirradiation WR-2721 administration and post- or preirradiation Broncho-Vaxom administration in lethally whole-body gamma-irradiated mice were investigated. Combined modality treatments were more effective than individual treatments alone. The ameliorative influence of the combined radioprotection could be explained by the hemopoietic stem cell protection with WR-2721 and the stimulation by Broncho-Vaxom.
Similar articles
-
Radioprotective effects of WR-2721, Broncho-Vaxom and their combinations: survival, myelopoietic restoration and induction of colony-stimulating activity in mice.Int J Immunopharmacol. 1994 Feb;16(2):177-84. doi: 10.1016/0192-0561(94)90074-4. Int J Immunopharmacol. 1994. PMID: 8181906
-
Combined radioprotection by preirradiation peroral cystamine and postirradiation glucan administration.Folia Biol (Praha). 1991;37(2):117-24. Folia Biol (Praha). 1991. PMID: 1908392
-
Possibilities of the combined use of non-steroidal anti-inflammatory drugs and sulfhydryl compounds in radioprotection.Strahlenther Onkol. 1991 Mar;167(3):186-90. Strahlenther Onkol. 1991. PMID: 1849667
-
Radioprotection by biological response modifiers alone and in combination with WR-2721.Pharmacol Ther. 1988;39(1-3):247-54. doi: 10.1016/0163-7258(88)90068-x. Pharmacol Ther. 1988. PMID: 2849129 Review. No abstract available.
-
Effect of radioprotective agents on X-ray cataracts.Lens Eye Toxic Res. 1989;6(4):573-88. Lens Eye Toxic Res. 1989. PMID: 2562120 Review.
Cited by
-
Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review.Molecules. 2017 May 19;22(5):834. doi: 10.3390/molecules22050834. Molecules. 2017. PMID: 28534834 Free PMC article. Review.
-
Pharmacological Modulation of Radiation Damage. Does It Exist a Chance for Other Substances than Hematopoietic Growth Factors and Cytokines?Int J Mol Sci. 2017 Jun 28;18(7):1385. doi: 10.3390/ijms18071385. Int J Mol Sci. 2017. PMID: 28657605 Free PMC article. Review.