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. 1979 Jan;16(1):13-5.
doi: 10.1007/BF00423144.

Delayed progression of diabetic retinopathy by divided insulin administration: a further follow-up

E Eschwege, D Job, C Guyot-Argenton, J P Aubry, G Tchobroutsky

Delayed progression of diabetic retinopathy by divided insulin administration: a further follow-up

E Eschwege et al. Diabetologia. 1979 Jan.

Abstract

We have previously reported a slower rate of progression in the number of microaneurysms in insulin dependent diabetic patients treated by divided insulin injections when compared to patients receiving a single daily insulin injection [Diabetes 25, 463--469 (1976)]. This observation is strengthened by the present analysis which uses complementary data obtained after a further year follow up: the mean yearly increase in the number of microaneurysms was 9 +/- 1 in the single injection group and 3 +/- 1 in the multiple one (p less than 0.001).

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