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. 1995 May;166(5):650-3.
doi: 10.1192/bjp.166.5.650.

A self-rating scale for measuring neuroleptic side-effects. Validation in a group of schizophrenic patients

J C Day  1 , G Wood, M Dewey, R P Bentall
Affiliations

A self-rating scale for measuring neuroleptic side-effects. Validation in a group of schizophrenic patients

J C Day et al. Br J Psychiatry. 1995 May.

Abstract

Background: A study was conducted to validate a comprehensive self-rating scale for measuring side-effects of neuroleptic drugs.

Method: The Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), which includes 'red herring' items, was twice administered to 50 DSM-III-R schizophrenic patients, who were also interviewed using the UKU side-effect rating scale; 50 unmedicated controls also completed the LUNSERS:

Results: The test-retest reliability of the LUNSERS was good (r = 0.811, P < 0.001) as was its concurrent validity against the UKU (r = 0.828, P < 0.001). Scores correlated with chlorpromazine equivalent doses (r = 0.310, P < 0.02). ROC analysis demonstrated that the scale discriminated between patients and non-medicated controls, who scored differently for real side-effects but not for 'red herring' items.

Conclusions: The LUNSERS is an efficient, reliable and valid method of assessing neuroleptic side-effects.

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