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Case Reports
. 1995 May;42(5):483-6.
doi: 10.1111/j.1365-2265.1995.tb02666.x.

Familial prolactinoma

M Berezin  1 , A Karasik
Affiliations
Case Reports

Familial prolactinoma

M Berezin et al. Clin Endocrinol (Oxf). 1995 May.

Abstract

Background: Apart from the rare association with type I multiple endocrine neoplasia (MEN-1), familial types of prolactinoma have not been reported.

Patients and measurements: Eight hyperprolactinaemic patients in four families and 18 of their first and second-degree relatives (parents, children and grandchildren) were examined. Hormone levels were measured, as well as other biochemical parameters.

Results: Prolactinoma was diagnosed in more than one member of each of the four families.

Conclusion: Familial prolactinoma is a distinct entity which is probably due to a genetic mutation promoting lactotroph proliferation.

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Comment in

  • Familial prolactinoma.
    Sobrinho LG. Sobrinho LG. Clin Endocrinol (Oxf). 1995 Oct;43(4):511. Clin Endocrinol (Oxf). 1995. PMID: 7586628 No abstract available.

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