Comment on

• Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

  DeFronzo RA, Goodman AM. DeFronzo RA, et al. N Engl J Med. 1995 Aug 31;333(9):541-9. doi: 10.1056/NEJM199508313330902. N Engl J Med. 1995. PMID: 7623902 Clinical Trial.
• Metabolic effects of metformin in non-insulin-dependent diabetes mellitus.

  Stumvoll M, Nurjhan N, Perriello G, Dailey G, Gerich JE. Stumvoll M, et al. N Engl J Med. 1995 Aug 31;333(9):550-4. doi: 10.1056/NEJM199508313330903. N Engl J Med. 1995. PMID: 7623903