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. 1995 Jul 25;1263(1):99-102.
doi: 10.1016/0167-4781(95)00080-z.

Identification and analysis of a 'young' polymorphic Alu element

S S Arcot  1 , J J Fontius, P L Deininger, M A Batzer
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Identification and analysis of a 'young' polymorphic Alu element

S S Arcot et al. Biochim Biophys Acta. .

Abstract

A polymorphic Alu element belonging to a young subfamily of Alu repeats has been identified. Sequence analysis showed that this Alu element is flanked by perfect direct repeats and a 3' oligo(dA)-rich tail. The Alu element, designated A25, is deleted by 34 nucleotides at the 5' end and has a single CpG mutation compared to the human-specific consensus sequence. Using a PCR-based assay, we demonstrated that the A25 Alu repeat is localized to human chromosome 8 and is polymorphic in humans.

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