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Comparative Study
. 1995 Jul 30;32(5):1347-50.
doi: 10.1016/0360-3016(94)00603-I.

Electron beam therapy is not inferior to superficial x-ray therapy in the treatment of skin carcinoma

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Comparative Study

Electron beam therapy is not inferior to superficial x-ray therapy in the treatment of skin carcinoma

C Griep et al. Int J Radiat Oncol Biol Phys. .

Abstract

Purpose: To compare recurrence rates and cosmetic results after electron beam therapy vs. superficial x-ray therapy for nonmelanoma skin carcinoma.

Methods and materials: A retrospective analysis was performed on 389 histologically confirmed basal cell and squamous cell carcinomas of the skin, treated with either superficial x-rays or electron beam therapy, with regard to local control rates and cosmetics, as scored with an arbitrary three-point scale.

Results: The overall local recurrence rate was 4.9% (19 out of 389). For small tumors (irradiated surfaces < or = 10 cm2) a local recurrence rate of 2.2% was observed, both after electron beam therapy and after superficial x-ray therapy. Tumor size and previous treatment proved to be important prognostic factors with regard to control rate. The well-fractionated electron beam therapy yielded better cosmetic results than the large fraction superficial x-ray therapy.

Conclusion: Electron beam treatment is not inferior to superficial x-ray treatment and even better for larger tumors. The inferior results of electron beam therapy reported in literature might be due to technical factors, which are discussed.

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