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Case Reports
. 1995 Aug;41(2):183-5.

Minocycline-induced hyperpigmentation

P H Hung  1 , J B Caldwell, W D James
Affiliations
  • PMID: 7636458
Case Reports

Minocycline-induced hyperpigmentation

P H Hung et al. J Fam Pract. 1995 Aug.

Abstract

A 70-year-old man developed hyperpigmentation of his forearms, hands, fingernails, sclerae, ears, and teeth after 9 years of therapy with minocycline for acne rosacea. Minocycline is widely used in the treatment of acne vulgaris and uncommonly produces the side effect of hyperpigmentation. This effect does not appear to be dose-dependent and usually resolves within months to years after discontinuation of therapy. Discoloration of adult teeth, however, is generally permanent.

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