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. 1995 May;48(5):656-64.

[Study of metabolism of T-3761 in animal]

[Article in Japanese]
M Tai  1 , K Demachi, Y Simizu
Affiliations
  • PMID: 7637200

[Study of metabolism of T-3761 in animal]

[Article in Japanese]
M Tai et al. Jpn J Antibiot. 1995 May.

Abstract

The metabolism of T-3761 in mouse, rat, rabbit, dog and monkey was studied. Four metabolites, other than unchanged T-3761, were detected and identified as follows: T-3761 glucuronide; T-3761M1, adduct of glucose; T-3761M2 and T-3761M3, compounds metabolized at 1-aminocyclopropyl ring. In urine of mouse, T-3761 glucuronide was mainly detected, but in urine of other animals, T-3761 was mainly detected.

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