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Clinical Trial
. 1995 Jun;50(6):672-4.
doi: 10.1136/thx.50.6.672.

Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy

L J Burgess  1 , F J Maritz, I Le Roux, J J Taljaard
Affiliations
Clinical Trial

Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy

L J Burgess et al. Thorax. 1995 Jun.

Abstract

Background: A statistical audit of adenosine deaminase (ADA) in pleural effusions was undertaken.

Methods: ADA analysis, cytological and microbiological examinations, and differential cell counts were performed on 462 pleural fluid samples.

Results: ADA activity in tuberculous effusions was higher than in any other diagnostic group. At a level of 50 U/l the sensitivity and specificity for the identification of tuberculosis was 90% and 89%, respectively.

Conclusions: ADA activity remains a useful test in the evaluation of pleural effusions.

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