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Review
. 1995 Apr;6(2):63-72.
doi: 10.1006/scbi.1995.0009.

Cyclins, CDKs and cancer

J Pines  1
Affiliations
Review

Cyclins, CDKs and cancer

J Pines. Semin Cancer Biol. 1995 Apr.

Abstract

The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes. In this review I will attempt to show how perturbations in the known cell cycle regulators may play a part in the process of oncogenesis.

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