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Review
. 1995 Jun;30(3):393-7.
doi: 10.1007/BF02347517.

Hepatic failure in a case of multiple myeloma-associated amyloidosis (kappa-AL)

T Yamamoto  1 , N Maeda, H Kawasaki
Affiliations
Review

Hepatic failure in a case of multiple myeloma-associated amyloidosis (kappa-AL)

T Yamamoto et al. J Gastroenterol. 1995 Jun.

Abstract

We report a case of kappa-AL amyloidosis which rapidly developed hepatic failure in a 79-year-old Japanese female who was admitted to our hospital because of abdominal distension and loss of appetite. Laboratory examination revealed a marked deterioration of liver function with cholestasis and monoclonal gammapathy. At the time that the diagnosis of IgG-kappa type multiple myeloma was made, jaundice was advanced, with continuous gastrointestinal bleeding. The patient died of hepatic failure 2 weeks after admission. Needle biopsy of the liver revealed a diffuse, massive deposition of amyloid protein.

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