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Review
. 1995 Apr;5(2):181-6.
doi: 10.1016/0959-440x(95)80073-5.

Myosin structure/function: a combined mutagenesis-crystallography approach

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Review

Myosin structure/function: a combined mutagenesis-crystallography approach

K M Ruppel et al. Curr Opin Struct Biol. 1995 Apr.

Abstract

In the past year, the structure of the regulatory domain of scallop myosin has joined that of the chicken skeletal muscle myosin subfragment 1 and provided insights into the regulation of myosin function. Mutagenesis studies in a variety of systems have used the information provided by these structures to create mutant myosins to test models of chemomechanical transduction and its regulation.

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