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. 1976 Jun;28(6):505-7.
doi: 10.1111/j.2042-7158.1976.tb02775.x.

A model independent method for estimating the in vivo release rate constant of a drug from its oral formulations

D P Vaughan

A model independent method for estimating the in vivo release rate constant of a drug from its oral formulations

D P Vaughan. J Pharm Pharmacol. 1976 Jun.

Abstract

A simple equation by which the first-order release rate constant of a drug from its oral formulation can be calculated is derived. The derivation is independent of any hypothetical concepts of drug distribution or elimination.

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