Review
doi: 10.1016/0197-0186(94)00165-q.
The function of metallothionein
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- PMID: 7655345
- DOI: 10.1016/0197-0186(94)00165-q
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Review
The function of metallothionein
Neurochem Int.
1995 Jul.
Abstract
Since its discovery in 1957 metallothionein (MT) has remained a protein in search of a function. After 40 years of frustrating efforts, three areas of research point to its zinc cluster structure as the basis of its functional potential: (1) the regulation of MT gene expression by zinc-dependent transcription factors, (2) neuronal growth inhibition in brain, and (3) interactions with glutathione and zinc proteins.
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