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. 1975 Dec;33(2-3):165-72.
doi: 10.1016/0027-5107(75)90191-8.

The gene dosage effect of the rad52 mutation on X-ray survival curves of tetraploid yeast strains

K S Ho

The gene dosage effect of the rad52 mutation on X-ray survival curves of tetraploid yeast strains

K S Ho. Mutat Res. 1975 Dec.

Abstract

The mutation rad52 in the yeast Saccharomyces cerevisiae confers sensitivity to X-rays. The gene dosage effect of this mutation on X-ray survival curves of tetraploid yeast strains is shown. With increasing number of rad52 alleles, both a decrease in the survival for a given dose and a decrease in the survival curve shoulder width are observed. The generation of such a family of survival curves using three different mathematical models is discussed.

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