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Clinical Trial
. 1995 Oct;154(4):1335-8.

Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy

K J Ho  1
Affiliations
  • PMID: 7658533
Clinical Trial

Urinary beta-glucuronidase in screening and followup of primary urinary tract malignancy

K J Ho. J Urol. 1995 Oct.

Abstract

Purpose: The usefulness of urinary beta-glucuronidase in screening and followup of urinary tract malignancy was tested.

Materials and methods: The activity and concentration of urinary beta-glucuronidase were determined in 80 healthy subjects, 113 urology patients with no cancer, and 60 with transitional cell and 23 with renal cell carcinoma. Patients with cancer were followed for 3 to 33 weeks.

Results: The enzyme activity and concentration were significantly greater in the cancer group, including residual tumor or recurrence after therapy, than in the controls with excellent discrimination.

Conclusions: Urinary beta-glucuronidase was indeed useful in screening and followup of urinary tract malignancy.

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