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. 1995 May;58(3):217-21.
doi: 10.1016/0034-5288(95)90105-1.

Effect of a recent injection of purified protein derivative on diagnostic tests for tuberculosis in cattle infected with Mycobacterium bovis

M L Doherty  1 , M L Monaghan, H F Bassett, P J Quinn
Affiliations

Effect of a recent injection of purified protein derivative on diagnostic tests for tuberculosis in cattle infected with Mycobacterium bovis

M L Doherty et al. Res Vet Sci. 1995 May.

Abstract

The intradermal injection of avian and bovine purified protein derivative into 15 Mycobacterium bovis-infected cattle reduced the capacity of a second single intradermal comparative tuberculin test carried out seven days later to predict accurately the animals' infection status (P < 0.001). In vitro lymphyocyte blastogenesis was also reduced (P < 0.05) but the in vitro production of interferon-gamma was unaffected.

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