Hematologic complications of diabetes mellitus

Abstract

In summary, hematologic abnormalities in diabetes affect the function, morphology, and metabolism of blood cells, and the coagulation system. These complications can contribute to the development of anemia, infection, and hypercoagulability in diabetic dogs and cats. Some hematologic changes, such as glycosylated hemoglobin and fructosamine, play an important role as markers of glycemic control. Hematologic changes also serve as important models for changes occurring in other tissues, such as cataract formation and nephropathy. Further study of blood alterations will enhance our knowledge of the biochemistry and pathophysiology of diabetes and diabetic complications and stimulate the development of effective preventative and therapeutic measures.