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. 1994 Nov;11(10):495-9.
doi: 10.1007/BF02216028.

Effects of pentoxifylline on human sperm parameters in vitro

I Mladenovic  1 , S Micic, R M Pearson, O Genbacev, N Papic
Affiliations

Effects of pentoxifylline on human sperm parameters in vitro

I Mladenovic et al. J Assist Reprod Genet. 1994 Nov.

Abstract

Purpose: Pentoxifylline was tested in three raising concentrations (0.7 mM/l, 1.5 mM/l, 3.6 mM/l) on human sperm cells in vitro.

Methods: On 143 samples, we examined drug effect on motile sperm concentration, grade of their motility, acrosome reaction and membrane status.

Results: Obtained results show improvement in motile sperm concentration, as well as in the grade of progression in the majority of samples.

Conclusions: Spermatozoa membranes as well as occurrence of the acrosomal reaction were not affected by pentoxifylline.

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