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Review
. 1995 May 15;3(5):417-20.
doi: 10.1016/S0969-2126(01)00172-1.

Proteasome: a complex protease with a new fold and a distinct mechanism

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Free article
Review

Proteasome: a complex protease with a new fold and a distinct mechanism

A Wlodawer. Structure. .
Free article

Abstract

The structure of the proteasome from Thermoplasma acidophilum introduces threonine proteases as a fifth class of proteolytic enzymes, and offers insights into the catalytic activity of this complicated piece of molecular machinery with its 14 active sites.

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