Proteasome: a complex protease with a new fold and a distinct mechanism
- PMID: 7663937
- DOI: 10.1016/S0969-2126(01)00172-1
Proteasome: a complex protease with a new fold and a distinct mechanism
Abstract
The structure of the proteasome from Thermoplasma acidophilum introduces threonine proteases as a fifth class of proteolytic enzymes, and offers insights into the catalytic activity of this complicated piece of molecular machinery with its 14 active sites.
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