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. 1995 Jul;33(7):1784-6.
doi: 10.1128/jcm.33.7.1784-1786.1995.

Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada

J M Blondeau  1 , F E Ashton, M Isaacson, Y Yaschuck, C Anderson, G Ducasse
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Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada

J M Blondeau et al. J Clin Microbiol. 1995 Jul.

Abstract

Moderately penicillin-resistant Neisseria meningitidis is rare in North America. We report an outbreak of meningococcal disease in Saskatoon, Saskatchewan, Canada, with serogroup C N. meningitidis. The MICs of penicillin ranged from 0.12 to 0.25 micrograms/ml, and all isolates showing decreased susceptibility had identical genomic fingerprints when they were compared by pulsed-field gel electrophoresis. Our data indicate that N. meningitidis that is moderately resistant to penicillin is prevalent in Saskatchewan, Canada.

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