Effects of submaximal physical exercise and immobilization in bed on the adenine nucleotides concentration in human blood platelets
Affiliations
- PMID: 7670130
Item in Clipboard
Effects of submaximal physical exercise and immobilization in bed on the adenine nucleotides concentration in human blood platelets
J Physiol Pharmacol.
1995 Jun.
Abstract
The effects of submaximal physical exercise (75% VO2max) and one month immobilization in bed on the adenine nucleotides concentration in human blood platelets were studied and compared. We have shown that after submaximal exercise and after immobilization in bed the concentrations of adenine nucleotides in blood platelets mainly ATP and ADP were decreased and probably caused by the stimulation of platelet secretory process. Thrombin which stimulated the release of 58.2% +/- 1.5% of total adenine nucleotides from control platelets, liberated decreased amounts of nucleotides from platelets after physical exercise and after immobilization in bed (39.9 +/- 2.1% and 23.6 +/- 2.03% of total, respectively).
Similar articles
-
Effect of bed rest on the adenine nucleotides concentration in human blood platelets.J Physiol Pharmacol. 1991 Dec;42(4):389-95. J Physiol Pharmacol. 1991. PMID: 1824298
-
Abnormalities of platelet adenine nucleotides in patients with myeloproliferative disorders.Thromb Haemost. 1979 Jun 30;41(4):787-95. Thromb Haemost. 1979. PMID: 483250
-
Adenine nucleotides in thrombin-degranulated platelets: effect of prolonged circulation in vivo.J Lab Clin Med. 1977 Sep;90(3):490-501. J Lab Clin Med. 1977. PMID: 894103 No abstract available.
-
[Release reaction and adenine nucleotide metabolism of blood platelets].Rinsho Ketsueki. 1976 Dec;17(12):1235-60. Rinsho Ketsueki. 1976. PMID: 798042 Review. Japanese. No abstract available.
-
Nucleotide metabolism of platelets.Annu Rev Physiol. 1985;47:677-90. doi: 10.1146/annurev.ph.47.030185.003333. Annu Rev Physiol. 1985. PMID: 3888083 Review. No abstract available.