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Comparative Study
. 1976 Jan;27(1):26-9.

[Model experiments on the effect of IgM- and IgG-antibodies on the reactivity of Treponema pallidum hemagglutination (TPHA)-test]

[Article in German]
R Volkerding, F Müller
  • PMID: 767301
Comparative Study

[Model experiments on the effect of IgM- and IgG-antibodies on the reactivity of Treponema pallidum hemagglutination (TPHA)-test]

[Article in German]
R Volkerding et al. Hautarzt. 1976 Jan.

Abstract

Fractionated sera of patients in different stages of syphilis were examined comparatively with the TPHA-FTA(IgM)- and FTA(IgG)-test. It was shown that the TPHA-test proved to be convenient for early immunologic diagnosis of syphilis. The TPHA-test includes not only IgG anti-treponemal antibodies but also IgM antibodies. In the early stage of syphilis a reactive result of TPHA-test can be related exclusively on treponemal specific IgM antibodies.

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