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. 1994;35(4):427-33.
doi: 10.1186/BF03548318.

Biological variability and measurement error variability in ocular biometry in samoyed dogs

B Ekesten  1
Affiliations

Biological variability and measurement error variability in ocular biometry in samoyed dogs

B Ekesten. Acta Vet Scand. 1994.

Abstract
in English, German

A-scan ultrasonography was performed in 40 healthy Samoyeds aged 2-5 years. Mydriasis and cycloplegia were induced in all dogs and 25 of the dogs were also sedated prior to the ultrasound examination. Five consecutive A-scans were taken on each eye and the intrasubject variance (measurement error) and true intersubject variance (true biological variation) were computed. The true biological variation was found to be of the same magnitude in both sedated and unsedated dogs, whereas the measurement errors were considerably larger in the group of unsedated dogs compared to the sedated ones. Magnitudes of the measurement errors for the anterior chamber depth and length of the vitreous body in the unsedated group were unacceptable. The sizes of the measurement errors in the sedated dogs were all within an acceptable range.

Ultraljudsundersökning av ögat med hjälp av A-scan utrustning genomfördes på 40 friska samojedhundar i åldern 2–5 år. Mydriasis och cykloplegi inducerades hos samtliga hundar och 25 av dessa hundar sederades även med medetomidin före undersökningen. Fem på varandra följande ultraljudsmätningar genomfördes på varje öga och variationen inom varje öga (mätfelet) och variationen mellan ögonen i respektive grupp (biologisk variation) beräknades. Den biologiska variationen var av samma storleksordning hos både sederade och osederade hundar, medan mätfelen var påtagligt högre i gruppen med osederade samojeder jämfört med de sederade. Mätfelen för främre ögonkammarens djup och glaskroppens längd i den osederade gruppen var av icke acceptabel storleksordning, medan mätfelen för samtliga avstånd var inom godtagbara gränser för hundarna i den sederade gruppen.

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