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Review
. 1993 Jan;41(1 Suppl):57-63.
doi: 10.1016/0090-4295(93)90197-i.

DNA and RNA amplification in urology: the polymerase chain reaction

D E Riley  1 , J N Krieger
Affiliations
Review

DNA and RNA amplification in urology: the polymerase chain reaction

D E Riley et al. Urology. 1993 Jan.

Abstract

Polymerase chain reaction (PCR) technology is a promising molecular approach for diagnosis of genitourinary tract infections, inherited disorders, tumor-associated genetic alterations and tumor markers. Because it is based on exponential amplification, the technology is capable of ultimate theoretical sensitivity. Although not entirely free of technical limitations, PCR holds advantages over other diagnostic tests, including exquisite sensitivity, specificity, interchangeability and speed.

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